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The collation of spatiotemporal climatic data with
2019-04-28
The collation of spatiotemporal climatic data with epidemiological, clinical, and environmental data is a powerful approach to understanding associations between health outcome and climate exposure. Although climate data has been used to formulate disease models and produce predictions, Lowe and her
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Findings Between July and March we
2019-04-28
Findings Between July, 2013, and March, 2015, we enrolled 324 pregnant women (162 to each study group); 18 women were lost to follow up before delivery. Measurements of biomarkers made more than 60 days before randomisation (17 participants) or more than 300 days after randomisation (26 participants
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Both stunting and environmental enteric dysfunction improve
2019-04-28
Both stunting and environmental enteric dysfunction improve with radical shifts in environment, such as migration or local economic development. This improvement is reflected to some extent by the smoothing of the seasonality of undernutrition reported by Nabwera and colleagues in these three Gambia
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IRF expression had previously been described as
2019-04-28
IRF1 expression had previously been described as a factor that contributes to susceptibility for HIV-1 infection [14]. Our findings evidenced a different expression modulation of this transcription factor in the two groups of DC according with the expression of the important Th1 driving cytokine IL-
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IL IL is another potential inhibitor of OBL
2019-04-28
IL-7: IL-7 is another potential inhibitor of OBL differentiation in MM that induces RANKL production by T lymphocytes [113] and mediates MM-induced OBL inhibition by down-regulating RUNX2 transcriptional activity [93]. IL-7 levels are increased in the marrow of MM patients and that IL-7 inhibited bo
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Introduction Pulmonary vein isolation PVI is an established
2019-04-28
Introduction Pulmonary vein isolation (PVI) is an established strategy of paroxysmal atrial fibrillation (PAF) ablation [1–3]. Radiofrequency catheters have been the standard for AF ablation; however, PVI using balloon-based ablation has been increasingly adopted by electrophysiology laboratories a
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El poema arranca de una contemplaci n del paisaje
2019-04-28
El poema arranca de una contemplación del paisaje en pleno mes de noviembre. El “verdor” de las siemprevivas contrasta con un panorama vegetal dominado por la “grisura” de la deshojadura otoñal. La mirada del yo poético se fija preferentemente “en las siemprevivas y en las plantas perennes”. Esta pe
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Undoubtedly hydroxyurea has a huge potential
2019-04-28
Undoubtedly, hydroxyurea has a huge potential for improving the quality of lives of people affected by sickle-cell anaemia in settings where frequent and probably unsafe blood transfusions are the current standard of care. However, attention needs to be directed towards the potential adverse effects
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Una participaci n de particular relevancia fue la de Hugo
2019-04-28
Una participación de particular relevancia fue la de Hugo Chávez en el Fsm 2006, pues su discurso puede considerarse una síntesis de la comprensión desde la política institucional latinoamericana de izquierdas sobre los movimientos sociales. En su discurso, Chávez convocó a01 la coordinación y a la
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The aim of this study was to
2019-04-26
The aim of this study was to determine the therapeutic relevance of blocking RANKL in Ewing\'s sarcoma by using OPG administered by non-viral gene transfer approaches in two models of human Ewing sarcoma in immunodeficient mice. OPG was administered using amphiphilic polymers constituted by blocks o
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Bone marrow resident Macs Osteomacs are located in
2019-04-26
Bone marrow resident Macs (Osteomacs) are located in canopy-like structures in endosteal and periosteal surfaces, above osteoblasts [6]; osteoclasts result from the fusion of several myeloid osteoclast precursors [7]. Osteomacs constitute approximately 17% of the bone marrow ACY1215 Supplier and th
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More recently Brugada et al
2019-04-26
More recently, Brugada et al. [131]. used flecainide to identify the full extent of low-voltage electrogram activity in the anterior RV and RVOT and targeted this region for RFA. In all 14 BrS patients, RFA eliminated abnormal bipolar electrograms, normalized ST-segment elevation on right precordial
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Introduction Hepatosplenic T cell lymphoma HSTCL is
2019-04-26
Introduction Hepatosplenic T-cell lymphoma (HSTCL) is a rare subtype of peripheral T-cell lymphoma, which is derived from cytotoxic T-cells typically expressing γδ T-cell receptor (TCR). It usually occurs in young men and is characterized by B symptoms such as a fever, weight loss and night sweats,
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Fig shows an example of RNRVAS in a dual
2019-04-26
Fig. 3 shows an example of RNRVAS in a dual-chamber pacemaker recipient with sinus node disease, with the pacemaker set in rate adaptive DDI-R mode pacing with an AV interval of 300ms and lower rate limit of 60ppm. The tracing shows sensor-driven DDIR pacing at 80bpm (V–V cholinesterase inhibitor l
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CT analysis of tumour bearing bones showed significantly
2019-04-26
μCT analysis of tumour bearing bones showed significantly increased bone density in animals receiving zoledronic acid, alone or in combination with doxorubicin, compared to PBS control. Our results confirmed that a single dose of zoledronic 740 Y-P caused sustained bone effects throughout the experi
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