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Bran is a byproduct of flour milling
2023-10-25
Bran is a byproduct of flour milling, typically utilized as a valuable component of animal feeds. Because of its attractive technological and health-promoting properties, it xec receptor has also been increasingly used in food manufacturing as a source of dietary fiber. Indeed, with the growing int
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br Introduction Heart failure HF is a
2023-10-25
Introduction Heart failure (HF) is a chronically progressive disease and one of the most important causes of morbidity and mortality worldwide despite recent improvements in its treatment [1], [2], [3]. The mortality and morbidity benefits of angiotensin converting enzyme inhibitor (ACEI) are wel
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The proinflammatory cytokines and chemokines including IL TN
2023-10-25
The proinflammatory cytokines and chemokines, including IL-1β, TNF-α and MCP-1, mediate acute and chronic inflammation and play a role in the development of hypertension [2, [51], [52], [53]], cardiovascular diseases [4, 54] and renal injury [55, 56] in animal models and humans. Concerning the possi
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br Concluding Remarks and Future Perspectives The
2023-10-25
Concluding Remarks and Future Perspectives The collective evidence from studies detailing the functions of AMPK in the neuromuscular system, combined with those in DMD, SMA, and DM1 surveyed in the present review, strongly suggests that AMPK is a central mediator of neuromuscular determination, m
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Kuda et al reported that the activity of aminopeptidase A
2023-10-25
Kuda et al. (1997) reported that the activity of aminopeptidase A (ApA) but not aminopeptidase B (ApB) nor aminopeptidase N (ApN) was decreased in plasma from patients with Alzheimer's disease (AD). More recently Puertas et al. (2013) reported that the activities of plasma ApA, ApB, ApN and IRAP wer
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This study demonstrates numerical alterations of creatinine
2023-10-25
This study demonstrates numerical alterations of creatinine levels potentially reflecting ongoing or even higher myocardial contraction of the LAA after successful LAAC. Creatinine is the direct breakdown product of creatine in muscle, the key metabolite for energy supply during muscular and myocard
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Herein we employ an adapted targeted quantitative proteomic
2023-10-25
Herein we employ an adapted targeted quantitative proteomic isotope dilution method, developed in our laboratory [[18], [19], [20], [21]], to quantify membrane transporters in fresh lung from five donors, in four immortalized human lung cell lines and in three control cell lines. We quantify twelve
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Lee et al have demonstrated that
2023-10-25
Lee et al. have demonstrated that APPL1 associates with AdipoR1 in Hek293 BET bromodomain inhibitor where both proteins have been overexpressed with suitable tags [16]. In contrast to recent data the formation of this complex is not enhanced by exogenous adiponectin [16], [33]. Knock-down of APPL1 r
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The obtained results indicate that even when the
2023-10-25
The obtained results indicate that even when the impairment of the same forms of memory are present, amnesia can develop in different ways. Impairment of memory reconsolidation in the conditioned food aversion model through both the serotonin receptor antagonist and the antagonist of NMDA glutamate
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LIMKi 3 In eukaryotes class III ACs
2023-10-25
In eukaryotes, class III ACs (including GCs) are almost universally present, with the noteworthy exception of higher plants. Our dataset comprises 9690 sequences of class III nucleotide cyclases from 710 eukaryotic species. Approximately 80% thereof belong to subclass IIIa and 10% to subclasses IIIb
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br Conclusions Several lines of evidence
2023-10-25
Conclusions Several lines of evidence have been established, which support the adenosine kinase hypothesis of epileptogenesis, which is based on a sequence of events leading from acute bromophenol blue injury to initial downregulation of ADK, rise in extracellular adenosine, changes in astrocyti
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br Results br Discussion The actin cytoskeleton
2023-10-25
Results Discussion The Avasimibe cytoskeleton is a highly attractive target for many bacterial toxins, owing to its role in activation and locomotion of immune cells, secretion of humoral response factors, and maintenance of protective barriers at the cellular (sub-membrane cytoskeleton) and
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The altered frequency of CD T cells
2023-10-24
The altered frequency of CD4+ T MRT67307 HCl in 5-LO−/− mice led us to hypothesize that these leukocytes could be exerting a primary control of the inflammatory response. In fact, the lack of 5-LO resulted in the accumulation of CD4+CD25+ cells expressing Treg markers. It is plausible to speculate
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The obtained results indicate that even
2023-10-24
The obtained results indicate that even when the impairment of the same forms of memory are present, amnesia can develop in different ways. Impairment of memory reconsolidation in the conditioned food aversion model through both the serotonin receptor antagonist and the antagonist of NMDA glutamate
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br Research perspective In vitro and in vivo
2023-10-24
Research perspective In vitro and in vivo studies have demonstrated that increased LPA/ATX signaling contributes to cancer initiation and progression. Recent findings on the role of non-tumoral ATX in cancer progression and metastasis highlighted a new functional contribution for the microenviron
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